Insufficient or too abundant supply, the mother, but the father, can promote the tendency to obesity and diabetes in her children and grandchildren!The power of parents and diabetes children and grandchildren

If it is known that the diet of the mother during her pregnancy is essential in the development of the child, and may influence the trend of obesity and diabetes type 2, it was not known until now what mechanisms, and we do not doubt that the grandchildren would be affected in turn.

The power of parents and diabetes children and grandchildren

The epigenetic inheritance Diabetes

A joint study of the Belgian, Italian and German researchers became interested in the epigenetic mechanisms that can influence the transmission of type 2 diabetes Epigenetic modifications, acquired alter the chromosomes of people with diabetes, and these changes are then transmitted to the offspring over generations. This character transmission mechanism acquired profoundly changed in recent years, the idea that we had of the laws of genetics. So we compared the chromosomes of people with and without diabetes diabetes type 2. Observation focused on the cells of the pancreas that regulates the level of sugar in the blood by its insulin secretion. It showed significant differences regarding epigenetic markers between the two groups of individuals.


Several studies show that the power of the mother during pregnancy , and perhaps diet before this pregnancy , lead to epigenetic changes, which are transmitted to the child, and which cause a predisposition to diabetes .


Birth weight and diabetes

In the UK, in the 80s, a study on the emergence of diabetes had focused on the relationship between the disease and the individual weights at birth and revealed, through birth records held several years earlier that infants who weighed less were, as adults, more resistant to insulin in the regulation of a strong level of glucose in their blood and thus were more likely to develop diabetes. The renewed experience in Alsace, in the 90s on younger people and intervals of several years, led to the same conclusion and confirmed that insulin resistance increases with age in children born with low weight. The relationship between the power of the mother during pregnancy and the child’s weight at birth has been established by further research and shows the interest of the attention to be on the diet of pregnant women .


Diet and Diabetes: a much older relationship

An epidemiologist at Inserm became interested further in this relationship between the power of the mother before the birth of his child and was able to show that it dates back several generations back and not just about the mother. Studies in Sweden and the Netherlands, using records on crop quality since the nineteenth century, have established that the risk of having diabetes was directly related to the power of fathers and mothers. In fact, children whose parents or grandparents have experienced periods of famine or abundance during their pre-puberty for men, and pregnancy for women, were more or less predisposed to have diabetes type 2 in adulthood. This also overlaps what has been called the “cohort hunger” in the Netherlands. In 1944, the inhabitants of Amsterdam suffer a drastic starvation. Girls born to starving mothers have been studied since 1994, and these girls have a higher risk of diabetes. More recently, we investigated the epigenetic marks in this cohort of hunger: they were indeed present, and transmitted over at least two generations.


In conclusion, it is not advisable to starve during pregnancy , or even before pregnancy, or eat excessively because these pipes could resound on his children and grandchildren. This advice also applies to men, who also can transmit their dietary errors to their offspring.


Of course, today we do not suffer real hunger, but harsh regimes are equivalent, and the boost that follows the product generally also its effects. Ladies and gentlemen, making plans , you’re hurting, but you also do your children!

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